These can be taken with other medication, alcohol etc and are not intended to make you drowsy. (read the instructions for use). I find they help on those long haul trips when you don't want to waste a couple of days getting over the flight. Drinking plenty of water and regular stretching and walking will help also.
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I take the tablets 2 hourly on the flight and on arrival right up until bedtime. Don't be tempted to have a mid afternoon nap on arrival. Change your watch to local time and eat and sleep when the locals do . It'll help you get used to the change of time.
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